Ned A Porter Selected Research

trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane Dihydrochloride

1/2016	Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis.
10/2011	Novel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome.

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Ned A Porter Research Topics

Disease

28	Smith-Lemli-Opitz Syndrome 01/2021 - 02/2010
9	Atherosclerosis 01/2017 - 01/2004
8	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2018 - 02/2003
7	Inflammation (Inflammations) 11/2021 - 05/2008
4	Pneumonia (Pneumonitis) 01/2022 - 09/2009
3	Asthma (Bronchial Asthma) 01/2022 - 09/2009
3	Neuroblastoma 01/2020 - 02/2010
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2020 - 05/2016
3	Neoplasms (Cancer) 02/2013 - 01/2005
3	Cardiovascular Diseases (Cardiovascular Disease) 10/2008 - 02/2007
2	Neurodevelopmental Disorders 01/2021 - 10/2013
2	Desmosterolosis 01/2019 - 09/2014
2	Retinal Degeneration 01/2016 - 06/2012
2	Dehydration (Water Stress) 10/2014 - 09/2002
1	Hyperplasia 10/2022
1	Airway Remodeling 01/2022
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021
1	Huntington Disease (Huntington's Disease) 01/2019
1	Hypertrophy 01/2016
1	Parkinson Disease (Parkinson's Disease) 10/2014
1	Alzheimer Disease (Alzheimer's Disease) 10/2014
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2014
1	Breast Neoplasms (Breast Cancer) 02/2013
1	Leukemia 03/2011
1	Colorectal Neoplasms (Colorectal Cancer) 03/2011
1	Cerebrotendinous Xanthomatosis 02/2010
1	Chondrodysplasia Punctata (Stippled Epiphyses) 02/2010
1	Hepatocellular Carcinoma (Hepatoma) 12/2009
1	Colonic Neoplasms (Colon Cancer) 02/2008
1	Hypercholesterolemia 01/2007
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2006
1	Disease Progression 02/2003

Drug/Important Bio-Agent (IBA)

21	7-dehydrocholesterolIBA 01/2021 - 02/2010
20	CholesterolIBA 01/2021 - 11/2005
16	OxysterolsIBA 11/2021 - 02/2010
10	LipidsIBA 10/2019 - 01/2004
6	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 08/2012 - 01/2005
6	Free RadicalsIBA 01/2010 - 01/2004
5	SterolsIBA 01/2020 - 01/2017
5	7-dehydrocholesterol reductaseIBA 01/2019 - 11/2010
5	Proteins (Proteins, Gene)FDA Link 10/2018 - 10/2008
4	OzoneIBA 11/2021 - 10/2014
4	Phospholipids (Phosphatides)FDA LinkGeneric 01/2017 - 02/2007
4	LDL Lipoproteins (beta Lipoproteins)IBA 01/2017 - 01/2004
4	AntioxidantsIBA 01/2017 - 02/2003
3	EnzymesIBA 01/2019 - 11/2010
3	Biological ProductsIBA 01/2017 - 11/2010
3	Oxidoreductases (Dehydrogenase)IBA 01/2017 - 06/2011
3	Fish OilsIBA 09/2009 - 10/2007
2	Air Pollutants (Pollutants, Air)IBA 11/2021 - 01/2020
2	Pharmaceutical PreparationsIBA 01/2020 - 09/2006
2	DesmosterolIBA 01/2019 - 10/2018
2	AldehydesIBA 10/2018 - 02/2007
2	oxidized low density lipoproteinIBA 01/2017 - 01/2004
2	low density lipoprotein inhibitorIBA 01/2017 - 11/2005
2	cyclopentenoneIBA 01/2017 - 09/2002
2	CytokinesIBA 11/2016 - 09/2009
2	trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane DihydrochlorideIBA 01/2016 - 10/2011
2	Biomarkers (Surrogate Marker)IBA 01/2013 - 06/2011
2	Docosahexaenoic AcidsIBA 09/2009 - 10/2007
2	Eicosapentaenoic AcidIBA 09/2009 - 10/2007
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 09/2009 - 10/2007
1	5-alpha Reductase InhibitorsIBA 10/2022
1	GlucocorticoidsIBA 10/2022
1	Dihydrotestosterone (Androstanolone)IBA 10/2022
1	SteroidsIBA 01/2022
1	Small Interfering RNA (siRNA)IBA 11/2021
1	Vitamin E FDA LinkGeneric 01/2021
1	Antidepressive Agents (Antidepressants)IBA 01/2021
1	Trazodone (Trittico)FDA LinkGeneric 01/2021
1	Antipsychotic Agents (Antipsychotics)IBA 10/2019
1	Aripiprazole (Abilify)FDA Link 10/2019
1	ManganeseIBA 01/2019
1	5,6-secosterolIBA 10/2018
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2017
1	ATP Binding Cassette Transporter 1IBA 11/2016
1	Liver X ReceptorsIBA 11/2016
1	Ergosterol (Lumisterol)IBA 05/2016
1	Retinaldehyde (Retinal)IBA 01/2016
1	Peptides (Polypeptides)IBA 10/2014
1	Amino Acids FDA Link 10/2014
1	Tocopherols (Tocopherol)IBA 01/2014
1	StreptavidinIBA 02/2013
1	Biotin (Vitamin H)FDA Link 02/2013
1	EstersIBA 01/2013
1	cholesta-5,8-dien-3 beta-olIBA 01/2013
1	7-ketocholesterolIBA 09/2011
1	Acetylcysteine (Siran)FDA LinkGeneric 03/2011
1	Acetaminophen (Paracetamol)FDA LinkGeneric 12/2009
1	Prostaglandins EIBA 09/2009
1	OvalbuminIBA 09/2009
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 09/2009
1	ProstaglandinsIBA 09/2009
1	F2-Isoprostanes (F2 Isoprostanes)IBA 09/2009
1	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 02/2008
1	Oxidants (Oxidizing Agents)IBA 01/2007
1	LigandsIBA 09/2006
1	alpha-Tocopherol FDA Link 11/2005
1	NeuroprostanesIBA 09/2002

Therapy/Procedure

1	Off-Label Use 01/2021